Analgesics
Name
CO-CODAMOL CODEINE TRAMADOL |
Effect
Compound analgesic of codeine and paracetamol Alkaloid opiate, converted to morphine in the liver. Binds to opioid receptors in the brain. Causes drowsiness and depresses breathing. Centrally acting synthetic analgesic, a very weak μ-opioid receptor agonist, induces serotonin release, and inhibits the reuptake of norepinephrine. |
Uses
Pain relief Reduces perception of pain. Suppressing coughs. Pain relief |
Dose
15/500mg & 30/500mg are prescribed doses in UK (8/550 & 12.8/500 available OTC) 15-60mg every 4-6hrs 50-100mg every 4-6hrs |
Side effect
Constipation, skin rashes, dizziness, sedation, shortness of breath, hypersensitivity reaction, fainting (syncope or near syncope), nausea and/or vomiting, confusion, loss of short-term memory, drowsiness, changes in blood, allergic reactions, euphoria, dysphoria, abdominal pain, pruritus (itching), easy bruising, bleeding gums, dry mouth and addiction. DO NOT TAKE WITH OTHER MEDS CONTAINING PARACETAMOL. Lightheadedness, dizziness, nausea, vomiting, shortness of breath, and sedation. Other side effects include allergic reactions, constipation, abdominal pain, rash and itching. Alcohol and other sedatives further impair brain function when taken with codeine. CHRONIC USE CAN CAUSE DEPENDANCE. Nausea, vomiting, sweating, itching and constipation. Withdrawal symptoms include; uncontrollable nervous tremors, muscle contracture, and 'thrashing' in bed (similar to restless leg syndrome). |