Anti-Ulcer
HIGH DOSES AND LONG-TERM USE CAN INCREASE THE RISK OF DEVELOPING OSTEOPOROSIS
Name
OMEPRAZOLE LANSOPRAZOLE RANITIDINE |
Effect
Protein pump inhibitor (PPI), blocks the enzyme in the wall of the stomach that produces acid. Reduces acid production for 5-6hrs PPI. Effects can last up to 24hrs Histamine-2 blocker that inhibits the action of histamine on parietal cells in the stomach (produce acid), thus reducing acid production. |
Uses
acid-inflammation and ulcers of the stomach and duodenum; GERD, erosive oesophagitis, heartburn, prevention of upper GIT bleeding and in combination with anti-biotics for treating H-Pylori Stomach and duodenal ulcers and GERD Promotes healing of stomach and duodenal ulcers, preventing ulcer reoccurrence, GERD and heartburn. |
Dose
20-40mg/day 15mg/day for 4-8 weeks 75-150mg twice/day Available OTC as Zantac |
Side effect
Diarrhea, nausea, vomiting, rash, headache and dizziness. Can increase blood concentrations of diazepam and warfarin by decreasing elimination in the liver. Diarrhea, nausea, vomiting, rash, headache and dizziness. Less likely to cause side effects than Omeprazole. Constipation, diarrhea, fatigue, headache, insomnia, muscle pain, nausea, and vomiting. May interfere with the effects of other drugs that require acid for absorption. |