Migraine
Name
SUMATRIPTAN |
Effect
Selective serotonin receptor agonist. Stimulates serotonin receptors in the brain which causes the muscles surrounding blood vessels to contract, leading to vasoconstriction (migraines are thought to be caused by vasodilation of blood vessels in the brain |
Uses
Acute migraines and cluster headaches |
Dose
25-100mg/day |
Side effect
Generally transient and mild. Pain or tightness in the chest or throat, tingling, flushing, weakness, dizziness, abdominal discomfort, sweating, nasal irritation, and injection site reactions. If taken with SSRI's it can lead to an increase in levels of serotonin in the brain and cause serotonin-related side effects. Should not be used by individuals with uncontrolled high BP as it can increase BP |